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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6418d3e570b9a3e4f678e41a312a588a46e03a2ee6d49e78a241c16970b76718' 
  AND token = 'F2SpDwlvOhy5zEx7fPE6ARt7990lCEgdjBEU7F/lR1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}