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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '196989251d9e793b4dced063f9f466867aca2fc186b8316293147d691e13a124' 
  AND token = 'vjf8SKD/doPaWyGv/e3Mw4V4EaUsXZVTg4y1wgGAaE4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}