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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ec58732e92e2453320e81d809e87781eb5aa7c13f06d7c721407e26f655f326' 
  AND token = 'hLoM9vM3dFTLe5YizMeYiUh4jcoAuwiSFWBVV28HlIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}