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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffbefd37c06dd31dfedc3963289608a54312dc2d09417027a3f4d4cfa6adab1b' 
  AND token = 'XRrf9xSbDU0OzSQ5lb7RgScsk+SR15qDXYCXhrc4uUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}