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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8eb8638228b61a47564b197c81cbb666f116e65d57a47240b1fec14ba13bbb72' 
  AND token = 'eq5jxxz6D+Z16Q3P8CxgYCrHBefRed9XD83je2W1dPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}