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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1442b6a4ccfb34d526cd0a1da5a5ed83d73f606e754670c6339a7f8fdeea07c2' 
  AND token = 'oRXESDHLm4t4dUGyaYb5eVHgnQLB6nm7teyqUKA0H/U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}