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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '521405e0828297c6b45987febb9d39d2e012f2ae6a1f06d34121d14e032716c3' 
  AND token = 'r2RO3rOo3ARRLQSa6so56jo57fqnZS3GhEmMlDgi6z4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}