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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f16cb8721f43b829f6c5c12f1d89492fff2cc369a66fbb0d6e1ff46194db0e02' 
  AND token = '/0ewpwExZTQcwhVnEKwLZPBjYrt70YlWQF0McYtLgls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}