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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2c2a896b2a1f7b44df1d8601df1f69fa6a2145ca9b90e95a6492bb4d05f6f11' 
  AND token = 'qIy+XMJ6xRgWXGak7lUsWA6Vgj/v9lUSaZRlnGoHamw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}