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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70ed066f69667e5c790bfafc6d1ae50a8de9c1aac363dd40f095bb4e3abba8af' 
  AND token = 'b6B6BKXIkxiKuncsFQ9Pnvifj1mGTdaw5xPwNRXEw74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}