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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11e4ef1ed86b92708916fe5f29d622cbdf042e0d8d47d61f08958fd65b88aa59' 
  AND token = 'Nlx1iDku3eg3kxbkpQvn9chSmWImlo8gPiGp+n4o+wY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}