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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '180bdab8c692f10bbe1809539f0a71361598391a03d19630b1fcd53a91c899a1' 
  AND token = 'FQdBFgZ94faDoJlP9h2n488zSelsCxuC2JvCH9/iddM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}