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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cf0a874062d51266652d91bba68b8f7ed2d4c52c3c9bdb41768071ff17d6d7b' 
  AND token = '9TXP/Dkt8IYtXKv9KrKyWAsjg5cf54xA7Fa/8sNHPQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}