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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f3601b1c8b143bb6e950a65e1a831c9d4c57171634cd3aa6d4128d83eccc56d' 
  AND token = 'uo7QXDFi3oCPy4NtgyoZmMitosBnbxaeKvhdM84pnZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}