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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50617ac298a57e3cf1d671c48286c8a18d10f8c7d6045a6d9345556fe6384765' 
  AND token = '/bFOIPejRL37Qr3PWWdgoSmy+cgwV8dRIcVt1HcomLw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}