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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb6aa111c18168f9f2f531409030f0ab56b667e0568c4ab0a5e5dd2f36682533' 
  AND token = 'i7mcIxpOUlPRbzFSSq00WAsV2x89ZQyWzdOoJ84cQRY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}