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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8561ac3ecc6a8c0f81377b66db283640ff3ea3416b6a1b9c4d8a5f8fe1329de' 
  AND token = '1jRK1jJIMgZAWGOrSikH22UExdvHu4cQydeozDieW/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}