SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41e4d4d87b266a3f89f8b2f4359ff6c12b3f8538ffe2474a0dd2603e48737e36' 
  AND token = 'mDduPESmrIW9NR9nuss2vF1zZGVw11s0+dIAKnJAu7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}