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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b1f5cb396ffc6548ab49b936f6c100b5758cc9324358cba5e66ce7247b1a1c8' 
  AND token = '1/LTEjIK2yS/aZD05ZHcOSg4/HcSZF2foHEc913ZP4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}