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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fbfcff83af21cd7ad07cd38d6f8da3e3904afb1e20651e2f0a8615d816a07372' 
  AND token = 'xMWpAchbJQtto80zrZjjjV4jNZcVs1uFHWXoTqXIt5E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}