SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '644bc799b259f17a85686e3dbbbea69239f77f674f9e203244da691ff8f45c12' 
  AND token = 'YRVDWCnZ+c+CkuDZ5Nj8L6F/qen12I96/BL98YbgW9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}