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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b95f799f93b7dd488f132178ef4aa8673b61ba908694ad8f0e187851836ca7f' 
  AND token = 'zYdV9WPkiwBpEztoP9ZYd/oDQ+3PeqVzS19GmCN7UA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}