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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '647f7fa5cdad1b58be6cefa5c3fe2f812a4529f401c1bd8033df06353d9e67a6' 
  AND token = 'RGMZwmypx2yxZFqeDTPcL8f+6EFHAisk0HR1Sk6LxU8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}