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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53fc2c6271b965ca42c6d59b276404e12cbaaa9dbc32354505b4a9599e311dca' 
  AND token = 'q1eLox4lXb37xYgrtMY/8gsz/ToCjwHzhe3jsLGNgHw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}