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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e04ba99b6f63abe412ed4e74d4b2f36d3b184af0e6330ff06c4b80148757202' 
  AND token = 'rPRoMFX288eirftukJmLsDfFOcHUP4ymuqie7dyMJTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}