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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73b65b26c37347b2e17a3167122bc62fb08f1d9720bc77a7f949721cf4205746' 
  AND token = 'KtfCtNxWeiPcDxujwwNyFI4O3s4byemYglT/UxuMeQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}