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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c7a1b20159c2923059cf0ed17aaf726c261f221e7f37b6c46cc41c600bf6180' 
  AND token = 'IBu54hQCyY+CAzX9mTHf9TAJHmdiNL5OfINwLx10jqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}