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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '366601c410e5051e30d0f0d94335f381d6ed3a2f854504c33bc5c1aabdad9b81' 
  AND token = '4fVWJV/ceyfLfFzcbNoIfgjFDEKGv80aOi2NnKii8JQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}