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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc49a7d6de20bd7eb644c3f1b4ba13733b19df554a6324f1d9272b1c7891d2d1' 
  AND token = 'bUzWf0hDH1zuZY5i9NxyOLzKvrtQSZHCxTrSD1lwRYI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}