SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7150cd56cdf4ddcea44d84b317e004b2fd41a937f08971136dede7c5ba3ba4a' 
  AND token = 't2Ul+t6+6GO7UjVq8rXC1fkUjPtHoGQReBN7wmlySAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}