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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c8340d62fd3110219f4a092bcae1addaa3b3cf0526b8fa6618938d7e0cbc558' 
  AND token = 'zMWh5E9pG7sYpamI+DT+CmTKEND1CMfYjuy6A2hcrdg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}