SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c06bb1fab12294d73ea16c52cf4d91b9cf790a6d69285ce934e4d013cca04ef' 
  AND token = 'lMqOiT+qKE4Hud3X21OHqWiw2fqAsfn0MhZMQEo/nVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}