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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c543f76aad1b359950e344f7331575b2e00651e6f80c8d6d057f61d31edbb604' 
  AND token = 'GzB9zl9BZ0vKTX7ImCmwIhEWpmR5FzrEG0bSW1ZN2nY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}