SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '949a9108b35f113f5f0b1ad2c7eb0d617cae7dc2007d6ddb195405e4f96c6279' 
  AND token = 'lb0UBja9GtSOvIRzyr1PMUJRf/OdmfsNBhzUg83w/VQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}