SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1673774e41a5e0936ad3edb582fa43deb0018b6102acaded0fd64dbeafacc350' 
  AND token = 'v3UgX7z+s4igYwemTtJy04fOtyzTsD3aoK3T0fQQNUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}