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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2b759746cb55c34241ac13b7dd200e22ed4882306a33b9757f828b03eb48d53' 
  AND token = 'AB2Vlu/FkmmaAeLaSWf0+UPzsT1oHcjMAQt+nNpBYBY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}