SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43f69de7b0ae6da68b4cf232f141af7dfea89e2dfb0968e3ee2632af1677209d' 
  AND token = 'dHnC/0uTdv61mXkr7PTTDGdaiaKRny6pee3ZCrDYGCc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}