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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f0a2d04e914458d5a781eb0e5bdc9f654c0cfbcd111897f8ec421863141174b' 
  AND token = 'SQ1WnEIj2i4FFD8kETlwS49VuWghYaOPsVRvHmC3Ps0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}