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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '053d5d11cc0758f2174fcad0d5a2e7d517be6f814fc9076aed6d8bc94b251b32' 
  AND token = 'Zp7P83LwfAE4CvbK3TkSGnrDTo0tRqOGKE2kxfg84pk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}