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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4643353bf42dfa2977308b6a202111b2eb921d2883ae41628fcfa8e1205a4de' 
  AND token = 'KWiv/rU0cooxlPpMS2DvrSeesnrTK4NyzeFEmG9bQbw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}