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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '296f838c591c93efe15f324758e19f14d22ed238d47698c944f5f858585025af' 
  AND token = '/yq2L8V0UrwreZhPSPe+8zqmiRb+0BeNtdKJBG8PTWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}