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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '458fa4a470d585e131d67026e54f73fa4005484e98c4f81efc9b3b6b2d538f53' 
  AND token = 'OnSYFk8qD8+zgC5TklSdVraGcrC39hD/MOnkqENA4Uc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}