SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20c3381268bd2d5b4ff36fe40b8e500470361f19ca2da2ac01f6c240551ffc14' 
  AND token = 'k9zyrwRuCirrJwbAQkkVaJQ7lI2vT0hrqDsL0vylrmo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}