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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5d5021ab9df98d57e101fb74629d8ec9583f1f46c46c483b09d36fb3e2d5106' 
  AND token = 'rT240yI37kbOoc0U3BS58TwU5kUWPxpkWV+lj+8oRcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}