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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c950e336678452442813c128adfa6ba7b61b9689a11e4ea06c1b7c03c3fc4430' 
  AND token = 'WMVaSxmgmwBwY6wmQ1sZwk+rYOY9LfbQ1FHaGrQywe0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}