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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04441761b3a3476335f7c1abcdacdd484b2a4e36d365c61b195b1d5b587868b9' 
  AND token = '/xTwfoow6hK+5Cy83foq2450W8kELJfptPTbXkoHzBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}