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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdf05ff39660e6e55cd95d78d33b5582717cf681edd464288c994e2be9bbeac5' 
  AND token = 'xRBm/pgZGgM2JmTTx2e3CtAFFi5fwd7OulUf2nbIiOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}