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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c597a9829fed64e1c19984d4349dc2201a5a0cdea33b3e528b674910593ef96e' 
  AND token = '+j1iOEplJPzEhS2aATJbrbZSpgOe3lTQkUHvQyDDsXk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}