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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1f2f8050dcf7c0251a429bf2287e7ee608f69b702e2f297b607c9f4d498691c' 
  AND token = '5/Axb7pBAX0kMz0CGmon9TZd+5ek+dx7MENnAawgYYg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}