SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd007fcb8380228a58994e6d3ff17853b3acf45ef31c52d14adbb2b85482b6d7f' 
  AND token = 'jKjcELLKwj0mXmOt9rOuGhjrwBSR1k5zlMYkJGIPdsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}